Table 3.
Effect of chronic ethanol consumption on the Emax (mN) and pD2 values for phenylephrine in endothelium-intact (E+) or denuded (E−) aortic rings from intact (non-OVX) and OVX female rats
| Groups |
Control |
Ethanol |
||
|---|---|---|---|---|
| Emax | pD2 | Emax | pD2 | |
| Non-OVX (E+) | 15.2±1.3a (12) | 7.00±0.06a | 15.1±1.2a (14) | 7.02±0.09a |
| Non-OVX (E−) | 20.3±1.6 (11) | 7.43±0.09 | 27.2±1.8b (11) | 7.67±0.09b |
| OVX (E+) | 19.0±1.6c (9) | 7.10±0.13 | 17.9±0.9a,c (7) | 6.90±0.10a |
| OVX (E−) | 19.2±1.2 (8) | 7.10±0.10 | 26.7±1.9 (9) | 7.27±0.07 |
Abbreviations: OVX, ovariectomy.
The number in parentheses indicates the number of animals per group. Values are means±s.e.mean.
a
Compared to corresponding E− group; compared to non-OVX (E+) group (ANOVA followed by Bonferroni's multiple comparison test, P<0.05).
b
Compared to respective control group.
C
Compared to non-OVX (Et) group.