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. 2007 Dec 1;36(2):559–569. doi: 10.1093/nar/gkm1029

Scheme 1.

Scheme 1.

Strategy for regulating mRNA (blue strand) digestion by RNase H (green surface rendering) using a photoactive asODN conjugate (red and magenta strands). Oligonucleotide structures were generated with Insight II (Accelrys, San Diego, USA). Representation of RNase H was generated from the PDB coordinates using PyMol (DeLano, W.L., 2002, on World Wide Web, http://www.pymol.org).