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. 2007 Dec 17;36(3):872–884. doi: 10.1093/nar/gkm1099

Figure 6.

Figure 6.

TrkB expression in the Dlx1/Dlx2 mutant retina. (A) Quantification of TrkB expressing cells in the Dlx1/Dlx2 mutant. At E13.5 there is no significant difference between the number of TrkB-expressing cells in the Dlx1/Dlx2 mutant retina compared with wild-type controls (T = 2.78, P = 0.05, N = 5). At E16.5 (A, asterisk) and E18.5 (A, plus) there is a significant reduction in the number of TRKB-positive cells in the neural retina (T = 9.53, P < 0.05, N = 5 for a 43% reduction at E16.5; T = 10.43, P < 0.05, N = 5 for a 30% reduction at E18.5). (B–G) Expression of TrkB in the wild-type and Dlx1/Dlx2 mutant murine retina. By E16.5 differences in the expression of TrkB are evident in Dlx1/Dlx2 mutant (F) as compared to wild-type retinas (C) with fewer TrkB-expressing cells identifiable in the GCL. This difference is also observed at E18.5 (D, wild-type; G, mutant). Error bars represent SDs. Scale bars: (A) 100 µM; (F, G) 50 µM.