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. 1999 Mar 30;96(7):4078–4083. doi: 10.1073/pnas.96.7.4078

Figure 5.

Figure 5

Expression of Bcl-2 in SN protects neurons from 6-OHDA toxicity. (A) Cell survival as estimated from cell counts of nigral FG+ cells 2 weeks after 6-OHDA lesion. THZ/S-bcl2 transfection resulted in a significantly greater number of FG+ cells surviving the lesion as compared with THZ.1 control transfected SN (n = 9 animals in each group, P < .05). (B) Cell survival as estimated from counts of TH-immunoreactive cells 2 weeks after 6-OHDA lesion. THZ/S-bcl2 transfection resulted in a significantly greater number of TH-immunoreactive cells surviving the lesion as compared with TSZ.1 control transfected SN (n = 9 animals in each group, P < .05). The experiment was repeated twice with the same results.