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Sample structure assessment that benefits from using the correct reference sphere size. The best-scored model of the target 1bbh in the moulder decoy set with (A) DOPE based on an underestimated radius of the reference sphere a of 16 Å. The Cα RMS error of this model is 15.4 Å. (B) When DOPE is calculated with the size a of 23 Å, it correctly scores the native structure better than any of the 300 decoys.
