Figure 4.

Folding rate dependencies. (a) Ca²⁺ dependence of the folding rate. (b) Metal ion dependence of the folding rates: (circles) Ca²⁺, (squares) Sr²⁺, (triangles) Mn²⁺, (inverted triangles) Ba²⁺, and (diamonds) Mg²⁺. The folding rate of the apo-form is marked by a dashed line. The continuous lines correspond to the best fits used to extract the dissociation constants of the MG- and T-states (given in Table 1), as described in Materials and Methods. The experimental errors are within the size of the symbols.