Table 3.

Dynamic light scattering analysis of EGFR-ICD–CEDANS

Protein samples were analyzed by use of DynaPro Molecular Sizing Instrument and Dynamics software. For each sample, the hydrodynamic radius (R_h) was determined from the measured translation diffusion coefficient by application of the Stokes-Einstein equation, and the molecular mass (M_r) was estimated with the supplied standard curve of M_r vs. R_h data. % Mass intensity for each sample was calculated after subtraction of solvent noise peaks. Bovine serum albumin was used as a control with the known molecular weight of 66 kDa.