Figure 3.
Role of SK channels in unstimulated and store-depleted cells. (A) Lack of effect of apamin on AP firing in a spontaneously active cell. (B and C) Activation of SK channels during sustained store depletion by GnRH or TG. Simultaneous measurements of Vm and [Ca2+]i changes in response to GnRH (B Left) or TG (C Left) before and during apamin addition. (Right) Asterisk denotes significant difference (P < 0.05; n = 3) from control. Double asterisks denote significant difference (P < 0.05; n = 3) between responses to TG or GnRH and apamin.