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Replication of SIV variants generated in human 293T cells.
| Virusa | JC-53B titerb IUc/ml | ELISA (p27)b ng/ml | IU/ngc | (fold difference from SIVmac239) |
| SIVmac239 | 1 × 103 | 306 | 3 | - |
| SIVmac239T | 6 × 103 | 101 | 59 | 20 |
| SIVmac18 | 1 × 103 | 117 | 9 | 3 |
| SIVmac18T | 3 × 104 | 65 | 461 | 154 |
aViruses were obtained simultaneously after transfection of 293T cells with equimolar amounts of DNA.
bAssays are described in Methods.
cInfectious units
