Table 5.
Comparison of mRNA responses by real-time PCR1.
| Genes | SIVmac239T/SIVmac239 (fold difference)2 |
| IL2 | 1.34 |
| IL4 | 1.76 |
| IL6 | -1.32 |
| IL7 | -1.41 |
| IL10 | -1.05 |
| IL12p40 | 1.09 |
| IL15 | -1.16 |
| IFNA1 | 1.13 |
| IFNα | 1.15 |
| IFNβ | 1.04 |
| IFNγ | -1.14 |
| Mx | -2.22 |
| TNFa | -1.11 |
| IRF1 | 1.09 |
| IRF2 | 1.05 |
| IRF3 | -1.09 |
| IRF4 | 1.09 |
| IRF5 | 1.13 |
| IRF7 | -1.27 |
| PU.I | 1.06 |
| SPIB | -1.05 |
1RNA samples were the same as used for microarray assay.
2Changes in cellular mRNA levels after infection by SIV with full length Env were compared with mRNA levels in cells infected by SIV with truncated Env and expressed in folds.
Note fold repression is indicated by a minus sign