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. 2007 Dec 20;8:115. doi: 10.1186/1471-2199-8-115

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Copyright © 2007 Pahari et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Phylogenetic (NJ) tree of SVSPs. Sequences (complete ORF) available from other pit vipers [47] and 11 isoforms (DQ464238–DQ464248) from this study (filled circle) were used. Tissue kallikrein-1 (P06870) is used as outgroup. The numbers on the branches indicate the bootstrap support values for nodes, and the horizontal bar represents number of substitutions per site. TLE, thrombin-like enzymes; KN, kininogenase; PA, plasminogen activator; PAI, platelet aggregation inducer; BCD, blood clot dispersion; X, activity unknown. Experimentally verified activities are shaded.