Figure 2.

Block of muscle and neuronal AcChoRs by strychnine. The first AcCho-current in each trace of Inset corresponds to the control current elicited by AcCho on muscle α₁β₁γδ, neuronal α₂β₄, or α₂β₂ AcChoRs. The second AcCho-current was evoked by simultaneous superfusion of AcCho plus strychnine. The third response is the recovered AcCho-current recorded 6 min after withdrawing the drugs. The plot corresponds to AcCho-current recovery from block by 200 μM strychnine. Data were normalized to the control AcCho-current before strychnine application. Strychnine was applied before (filled circles) or together with (open circles) AcCho. Data were obtained from the same oocyte expressing muscle α₁β₁γδ AcChoRs. The continuous lines are fittings to single exponential functions.