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RNase II crystals. (a) Thin plate-shaped crystals of wild-type RNase II from E. coli with dimensions 0.4 × 0.15 × 0.04 mm, crystallized in space group P21 (crystal form A). (b) Crystals of RNase II D209N with dimensions of 0.25 × 0.1 × 0.1 mm, crystallized in space group P65.