Table 2. Patient survival in dependence of several clinicopathological factors and HDAC isoform expression (n=150).

Characteristic	No. of cases	No. of events	Mean PSA-relapse-free time (±s.e.) in months	P-value
HDAC1 expression				0.256
Low	53	18	112 (±10)
High	97	41	97 (±9)
HDAC2 expression				0.004
Low	42	9	134 (±13)
High	108	50	86 (±7)
HDAC3 expression				0.089
Low	9	1	148 (±15)
High	141	58	101 (±7)
Pre-OP PSA				0.006
⩽10 ng ml−1	72	20	117 (±8)
>10 ng ml−1	73	37	75 (±10)
Age				0.336
⩽65	105	44	99 (±9)
>65	45	15	108 (±12)
pT stage				0.003
pT2	78	22	111 (±9)
pT3/pT4	72	37	84 (±10)
Histological grade (Gleason)				<0.001
Gleason sum 2–6	59	12	127 (±9)
Gleason sum 7	51	22	95 (±12)
Gleason sum 8–10	40	25	50 (±8)
R-status				0.006
R0	79	23	122 (±9)
R1	71	36	76 (±10)
Ki-67 index				0.010
⩽10%	95	34	104 (±8)
>10%	34	21	62 (±14)

HDAC=histone deacetylase.

P-values were calculated with the log-rank test.