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. 2008 Jan 22;98(3):619–626. doi: 10.1038/sj.bjc.6604198

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Copyright © 2008 Cancer Research UK

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Observed and expected mutation frequency and age. Indicated are the observed D7S1482 mutation frequencies with 95% CI for all 31 control subjects. Mutation frequency increases with increasing age (P=0.004, GLM) as indicated by the predicted estimate from the univariate statistical model (solid line).