Table 1. PCR, in situ hybridization and immunohistochemical results for paraffin specimens of human papillary thyroid carcinoma and nonneoplastic-adjacent tissues.
|
IHC of NF-κB p65
|
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
ISH
|
IHC
|
Cytoplasmic
|
Nuclear | ||||||||
| Case | Age, years | Sex | nPCR | Tumour | Adjacent-tumour | Tumour | Adjacent-tumour | Tumour | Adjacent-tumour | Tumour | Adjacent-tumour |
| 1 | 36 | M | + | + | − | − | − | + | − | + | − |
| 2 | 34 | F | + | − | − | − | − | − | − | − | − |
| 3 | 62 | F | + | + | + | + | + | + | + | − | − |
| 4 | 61 | M | + | + | − | − | − | + | − | − | − |
| 5 | 39 | F | + | + | NT | + | NT | + | − | − | − |
| 6 | 41 | F | + | + | + | + | + | + | − | − | − |
| 7 | 47 | F | + | + | + | − | − | − | − | − | − |
| 8 | 59 | M | + | + | + | + | + | − | − | + | − |
| 9 | 28 | F | + | + | − | + | − | − | − | − | − |
| 10 | 28 | F | + | + | − | − | − | − | − | − | − |
| 11 | 49 | F | + | − | − | − | − | − | − | + | + |
| 12 | 24 | F | + | + | + | − | − | + | − | + | − |
| 13 | 33 | F | + | + | − | − | − | + | − | − | − |
| 14 | 40 | F | + | + | − | + | − | + | − | + | − |
| 15 | 62 | F | + | + | NT | + | NT | + | − | + | − |
| 16 | 39 | F | + | − | NT | − | NT | − | − | − | − |
| 17 | 64 | M | + | − | NT | − | NT | + | − | + | − |
| 18 | 37 | F | + | + | NT | + | NT | − | − | − | − |
| 19 | 60 | M | + | + | − | + | − | + | − | + | − |
| 20 | 48 | F | + | + | − | + | − | + | − | + | − |
| 21 | 30 | M | + | + | NT | + | NT | + | − | − | − |
| 22 | 68 | M | + | + | NT | + | NT | + | − | + | − |
| 23 | 30 | F | + | − | NT | − | NT | + | − | − | − |
| 24 | 75 | F | + | + | − | + | − | + | − | + | − |
| 25 | 35 | F | + | + | − | + | − | + | − | − | − |
| 26 | 29 | F | + | + | − | + | − | + | − | − | − |
| 27 | 33 | F | + | + | − | + | − | + | − | + | − |
| 28 | 34 | F | + | + | − | + | − | + | − | − | − |
| 29 | 47 | F | + | − | − | − | − | + | − | − | − |
| 30 | 42 | F | + | + | − | + | − | + | − | + | − |
| 31 | 44 | F | + | + | − | + | − | + | − | + | − |
| 32 | 33 | F | + | + | + | + | − | + | − | + | − |
| 33 | 38 | M | + | + | − | + | − | + | − | − | − |
| 34 | 37 | F | + | + | + | + | − | + | − | − | − |
| 35 | 42 | F | + | + | − | + | − | + | − | − | − |
| 36 | 41 | F | − | − | − | − | − | + | − | − | − |
| 37 | 47 | F | + | − | − | − | − | − | − | − | − |
| 38 | 57 | M | + | + | − | + | − | + | − | + | − |
IHC=immunohistochemistry; ISH=in situ hybridisation; NF-κB=nuclear factor kappa B; nPCR=nested PCR; NT=no nonneoplastic-adjacent tissues.