Immunohistochemical study of hTRX in Tg mice. Immunoreactivity for hTRX was observed in cortex (A and C) and hippocampus (B and D). High-power view shows that hTRX exists in neurons, endothelial cells, and glial cells (C and D). hTRX immunoreactivity was not shown in WT mice (E and F). Magnification: A, B, E, and F, ×40; C and D ×200.