Fig. 2.

Changes in 2,7,8-trimethyl-2-(2'-carboxyethyl)-6-hydroxychroman (γ-CEHC) levels in rat urine after the oral administration of placebo or γ-tocopherol (γ-Toc). The rats were fed a vitamin E-deficient diet (control) or a NaCl diet for 4 weeks. In each group, one subgroup was administered a placebo, while the others were given 10 mg (γ10), 20 mg (γ20), 40 mg (γ40) of γ-Toc. After the oral administration of single dose of the placebo or γ-Toc, the rat urine was collected for 24 h (divided into 6 h periods) and then the γ-CEHC content was measured. The values are the mean ± SEM. of 4–6 rats, *p<0.05, **p<0.01 vs the control diet group at each time period.