Table 2.

Single-channel conductance and conductance ratios

	gNa, pS	gLi, pS	gLi/gNa	n
αS589A	6.1  ±  0.1	7.8  ±  0.3	1.3  ±  0.1	2
αS589A*	4.3  ±  0.2	5.9  ±  0.7	1.4  ±  0.2	3
αS589D*	1.7  ±  0.1†	1.5  ±  0.2†	0.9  ±  0.2	5
βS531A	5.4  ±  0.7	9.2  ±  0.5	1.7  ±  0.3	4
γS543A	3.3  ±  0.9	6.3  ±  1.1	1.9  ±  0.8	4
wt	5.2  ±  0.2	8.9  ±  0.7	1.7  ±  0.2	5
wt*	3.8  ±  0.7	6.0  ±  0.2	1.6  ±  0.3	3

^*, from outside-out patches; other data are from cell-attached patches. g_Na, g_Li, single-channel conductance of Na⁺ or Li⁺ inward currents, respectively. The SEM of the g_Li/g_Na ratio was calculated as the sum of the SEM of the fractional errors × the g_Li/g_Na ratio.  

^†, conductance of mutant different from wt (P < 0.01).