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. Author manuscript; available in PMC: 2008 Feb 23.
Published in final edited form as: Mol Cell. 2007 Feb 23;25(4):505–517. doi: 10.1016/j.molcel.2007.01.022

Figure 5. Equilibrium model of tRNA motions on the ribosome.

Figure 5

The two subunit ribosome (yellow) is shown bound to tRNA (blue) and mRNA (green). The three states observed, classified as classical, hybrid state-1, and hybrid state-2, are defined by the motions of tRNA acceptor stems with respect to the large subunit. The apparent rates of transition between states are identified as tabulated in Table 1 and Supplemental Table 3. Conformational changes of the ribosome that may be important to tRNA motions, as described in the text, are shown as changes in A, P, and E site color.