FIG. 3.

Inhibition of virus-induced CPE (34) by various polycations and polyanions. (A) Effects of the polycations protamine sulfate and DSTP 27 on the CVB3 PD-induced CPE in CHO-K1 cells. Increasing concentrations of polycations were added to confluent CHO-K1 cells immediately before virus application. Mean percentages of CPE reduction calculated from at least three experiments are shown. (B) Dose-dependent inhibition of CVB3 PD-induced CPE by the polycations PPS, heparin, and HS from different organs. CHO-K1 cells were incubated with increasing concentrations of polyanions and infected with CVB3 PD. Three independent tests were taken to calculate mean values.