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. Author manuscript; available in PMC: 2009 Jan 15.
Published in final edited form as: Bioorg Med Chem Lett. 2007 Nov 17;18(2):759–761. doi: 10.1016/j.bmcl.2007.11.044

Figure 1.

Figure 1

(A) Strategy for conferring ligand-dependent stability to any protein of interest (POI) by fusing the DNA sequence encoding a destabilizing domain (DD) to the gene encoding the POI. (B) Structures of the ligands for FKBP(F36V).