A, Time course of the dimerization reaction catalyzed by CrPrx1. The reaction mixture contained 2 μm CrPrx1, 300 μm vindoline, 400 μm catharanthine, and 330 μm H2O2 in 0.1 m MES, pH 6.8. B, HPLC chromatograms of the substrates of the dimerization reaction (0 min) and of the time point corresponding to a maximum yield of the dimerization reaction (30 min). V, Vindoline; C, catharanthine.