Table 2.
fHBP phenotypea | fHBP variant | Isolates, %b | Prototype strain | Predominant STc (ET) complex |
---|---|---|---|---|
111-000 | 1 | 70 | MC58 | ST-32 (ET-5) |
011-000 | 1 | 9 | 4243 | Heterogeneous |
011-100 | 1 | 10 | NZ98/254 | Heterogeneous |
Other v.1 | 1 | 11 | None | None |
| ||||
000-111 | 2 or 3 | 20 | 2996 | ST-35 complex |
000-110 | 2 | 24 | MD01158 | ST-41/44 (lineage III) |
000-001 | 2 or 3 | 12 | M1239 | ST-162 complex |
000-000 | 2 | 44 | RM1090 | Heterogeneous |
Pattern of fHBP monoclonal antibody (MAb) reactivity in the order JAR 1, 3, 5 (anti–variant [v.] 1 MAbs) and JAR 10, 11, 13 (anti-v.2 MAbs); 1 indicates reactivity, and 0 indicates no reactivity.
Among v.1 or among v.2 and v.3 isolates, respectively.
Multilocus sequence type (ST), per the Multi Locus Sequence Typing database (available at: http://www.mlst.net) [38]. “Predominant” implies that ≥50% of isolates had the specified ST.