Table 2.
HLA supertype specificity descriptions.
Supertype(s) | B pocket specificity | F pocket specificity |
A01 | Small and aliphatic | Aromatic and large hydrophobic |
A01 A03 | Small and aliphatic | Aromatic and basic |
A01 A24 | Small, aliphatic and aromatic | Aromatic and large hydrophobic |
A02 | Small and aliphatic | Aliphatic and small hydrophobic |
A03 | Small and aliphatic | Basic |
A24 | Aromatic and aliphatic | Aromatic, aliphatic and hydrophobic |
B07 | Proline | Aromatic, aliphatic and hydrophobic |
B08 | Undefined | Aromatic, aliphatic and hydrophobic |
B27 | Basic | Aromatic, aliphatic, basic and hydrophobic |
B44 | Acidic | Aromatic, aliphatic and hydrophobic |
B58 | Small | Aromatic, aliphatic and hydrophobic |
B62 | Aliphatic | Aromatic, aliphatic and hydrophobic |