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Schematic representation of the regulation of the DegU-regulon. A. Unphosphorylated DegU binds to the BRs containing the IR-like sequences in the flgB promoter or IR in the comK promoter. DegS phosphorylates DegU in response to some unknown signal. DegU-P binds to DR in the sacB, as well as probably to the bpr and aprE promoters. B. Alignment of DegU-recognition sequences. comK-IR and aprE-DR are shown in [19] and bpr-DRs are shown in [22].
