Table 7.
Results of bacterial gene point mutation assay. Cerium oxide - nanoparticulate. Summary of mean revertant colonies obtained
| Experiment 2 | |||||||||||
| Substance | Dose Level (μg/plate) | TA100 | TA1535 | TA102 | TA98 | TA1537 | |||||
| Mean ± S.D. | Mean ± S.D. | Mean ± S.D. | Mean ± S.D. | Mean ± S.D. | |||||||
| (-S9) | (+S9) | (-S9) | (+S9) | (-S9) | (+S9) | (-S9) | (+S9) | (-S9) | (+S9) | ||
| DMSO | 100 μl | 97 ± 14 | 132 ± 8 | 28 ± 6 | 30 ± 11 | 394 ± 9 | 380 ± 25 | 21 ± 5 | 38 ± 7 | 12 ± 10 | 15 ± 6 |
| Cerium Oxide Nano | 50 | 99 ± 19 | 123 ± 17 | 32 ± 2 | 29 ± 5 | 359 ± 28 | 397 ± 39 | 21 ± 4 | 33 ± 10 | 12 ± 1 | 13 ± 6 |
| 150 | 98 ± 20 | 127 ± 10 | 35 ± 6 | 40 ± 6 | 361 ± 32 | 391 ± 32 | 22 ± 4 | 32 ± 2 | 14 ± 7 | 12 ± 4 | |
| 500 | 84 ± 6 | 126 ± 11 | 35 ± 11 | 32 ± 4 | 382 ± 29 | 350 ± 7 | 21 ± 4 | 32 ± 5 | 14 ± 4 | 16 ± 4 | |
| 1500 (F) | 92 ± 8 | 133 ± 7 | 36 ± 8 | 36 ± 7 | 361 ± 43 | 313 ± 29 | 19 ± 5 | 37 ± 4 | 9 ± 3 | 12 ± 3 | |
| 5000 (F+P+M) | 95 ± 3 | 121 ± 22 | 28 ± 5 | 29 ± 3 | 371 ± 24 | 353 ± 36 | 19 ± 3 | 26 ± 3 | 9 ± 1 | 17 ± 2 | |
S.D. Standard deviation
F Film
P Precipitate
M Manual Count