Fig. 11.

Theoretical predictions of the distribution of microglia in a lane five cells wide that gave a Ca^2 + response, with an amplitude greater than 15% of maximum, following excitation of a single microglial cell at three different sites along the length of the lane, indicated by filled circles (∙). The dots indicate the positions of microglia in the lane. The diamonds (⋄) indicate microglia that gave a response following stimulation of the microglia near the left-hand end of the lane (sixth cell from the left at − 250 ), the open circles (∘) responses following stimulation of the microglia near the right-hand end of the lane (sixth cell from the right at 250 ) and the plusses (+) microglia in the centre of the lane (at 0 ). (A longer lane (800 ) has been used for this calculation.) The K_R values range from 25 to 45 μM for different microglia across each lane. Note that there is no overlap in the Ca^2 + wave domains of each stimulated microglial cell, the diamonds, crosses and circles designating discrete regions