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. 2007 Oct 23;4(1):47–59. doi: 10.1007/s11302-007-9076-9

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Fig. 5 — Propagation of Ca^2 + waves is blocked by the ATP-degrading enzyme apyrase. A and B show the extent of propagation of Ca^2 +, from the point of mechanical stimulation of a microglial cell, to other microglial cells in a lane. In each case, the top panel (a) shows the position of the mechanically stimulating micropipette and the lower panel (b) shows the microglial cells that gave a Ca^2 + signal (open circles) in response to mechanical stimulation at the arrow. A is the control and in B apyrase (60 units/mℓ; grade III, Sigma) was present with only the stimulated cell now giving a Ca^2 + transient. The calibration bar is 45

Inline graphic — Propagation of Ca^2 + waves is blocked by the ATP-degrading enzyme apyrase. A and B show the extent of propagation of Ca^2 +, from the point of mechanical stimulation of a microglial cell, to other microglial cells in a lane. In each case, the top panel (a) shows the position of the mechanically stimulating micropipette and the lower panel (b) shows the microglial cells that gave a Ca^2 + signal (open circles) in response to mechanical stimulation at the arrow. A is the control and in B apyrase (60 units/mℓ; grade III, Sigma) was present with only the stimulated cell now giving a Ca^2 + transient. The calibration bar is 45