Skip to main content
. Author manuscript; available in PMC: 2008 Feb 18.
Published in final edited form as: Mitochondrion. 2006 Mar 29;6(3):118–125. doi: 10.1016/j.mito.2006.03.002

Fig. 3.

Fig. 3

Depletion of C2-ceramide from the mitochondrial membrane restores the permeability barrier of the mitochondrial outer membrane. (a) Isolated mitochondria were incubated with 20 µM [14C] C2-ceramide for 15 min (black bar) or for 5 min followed by a 10 min incubation with a five molar excess of fatty acid-depleted BSA (white bar). The level of statistical significance from control (20 µM [14C] C2-ceramide for 15 min) are: ***, P≤0.001. (b) The same experiments as in (a) except using [14C] C16-ceramide. Results are a representative experiment from three independent experiments. Error bars are the standard deviations.