FIG. 1.

Predicted amino acid sequence of the EV homologues of VGF, VCP, and vSEMA. Shown are pairwise alignments of the predicted amino acid sequences of VGF (A), VCP (B), and vSEMA (C) from EV Moscow-3P2 and VV Copenhagen (18). Solid backgrounds represent amino acid differences and stars indicate stop codons. Solid triangles show signal peptide cleavage sites (SP). In the VGF sequence (A), the regions of higher sequence similarity to host EGF are underlined and the transmembrane anchoring domain is double underlined.