Table 1.
All children who received HAART | Treated for TB during study period | Not treated for TB during study period | p-value | |
Total number | 290 (100%) | 140#‡ (100%) | 150## (100%) | |
Gender | ||||
Male | 143 (49%) | 67 (48%) | 76 (51%) | 0.43 |
Age (months) | ||||
Range/median | 1–160/23.5 | 2–140/19 | 1–160/33.5 | 0.08 |
WHO HIV staging* | ||||
CD4 depletion | ||||
not significant | 22 (8%) | 4 (3%) | 18 (12%) | NA |
mild | 26 (9%) | 9 (6%) | 17 (11%) | 0.14 |
advanced | 31 (11%) | 10 (7%) | 21 (14%) | 0.06 |
severe | 211 (73%) | 117 (84%) | 94 (63%) | <0.001 |
Clinical stage | ||||
II | 15 (5%) | 1 (1%) | 14 (9%) | NA |
III | 128 (44%) | 50 (36%) | 78 (52%) | <0.01 |
IV | 144 (50%) | 89 (63%) | 55 (37%) | <0.001 |
Unknown | 3 (1%) | 0 (0%) | 3 (2%) | NA |
Weight categories | ||||
<60% EWA** | 43 (15%) | 29 (21%) | 14 (9%) | <0.01 |
60–80% EWA | 110 (38%) | 64 (46%) | 46 (31%) | <0.01 |
80–100% EWA | 92 (32%) | 34 (24%) | 58 (39%) | <0.01 |
>100% EWA | 25 (9%) | 6 (4%) | 19 (13%) | 0.01 |
Unknown | 20 (7%) | 7 (5%) | 13 (8%) | 0.22 |
Previous TB | ||||
1 episode | 76 (26%) | 19 (14%) | 57 (38%) | <0.001 |
≥2 episodes | 12 (4%) | 7 (5%) | 5 (3%) | NA |
*WHO, World Health Organization immunological classification of HIV-associated immunodeficiency in infants and children, 2006
**EWA, expected weight for age
# Includes 4 children subsequently excluded due to incomplete data
## Includes 5 children with BCG disease only, who were excluded from further TB analysis
NA – not applicable, sample proportions too small for Z test