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. 2007 Dec 27;9(6):R91. doi: 10.1186/bcr1840

Table 3.

Summary of diet effects on leptin and apoptosis signaling protein and mRNA expression levels

MT MFP
Leptin signaling molecules
 Leptin NC Inline graphic NC NC
 ObR NC Inline graphic NC Inline graphic
 ObRb Inline graphic Inline graphic Inline graphic Inline graphic
 Jak2 Inline graphic NM Inline graphic NM
 pSTAT3 Inline graphic Inline graphic NC NC
Apoptosis signaling molecules
 PARP (total) Inline graphic Inline graphic
 PARP (89 kDa) Inline graphic NC
 PARP (24 kDa) Inline graphic NC
 Caspase-3 activity Inline graphic Inline graphic
 Bax NC Inline graphic
 Bcl-2 NC NC
 Bcl-XL Inline graphic Inline graphic
 pAkt NC NC

Jak2, Janus kinase 2; MFP, mammary fat pad; MT, mammary tumor; NC, no statistically significant change; NM, not measured; pAkt, phosphorylated Akt; PARP, poly(ADP-ribose)polymerase; pSTAT3, phosphorylated signal transducer and activator of transcription 3. Solid arrows show protein expression and dashed lines mRNA expression.