Table 3.
Odds ratios and 95% confidence intervals for breast cancer risk associated with BsmI and Poly(A) genotypes, stratified by race and menopausal status
| Genotype | Menopausal status | Caucasian | African-American | |||||
| Case (%) | Control (%) | ORa (95% CI) | Case (%) | Control (%) | ORa (95% CI) | |||
| BsmI | B/B | Premenopausal | 164 (25.3) | 133 (25.8) | 1.0 (referent) | 38 (12.1) | 22 (9.6) | 1.0 (referent) |
| B/b | 244 (36.9) | 198 (36.0) | 1.1 (0.8 to 1.5) | 108 (34.6) | 90 (36.7) | 0.8 (0.4 to 1.4) | ||
| b/b | 247 (37.8) | 199 (38.1) | 1.0 (0.7 to 1.4) | 156 (53.3) | 126 (53.7) | 0.8 (0.4 to 1.5) | ||
| Any b | 491 (74.7) | 397 (74.2) | 1.0 (0.8 to 1.4) | 264 (87.9) | 216 (90.4) | 0.8 (0.4 to 1.4) | ||
| B/B | Postmenopausal | 114 (23.5) | 125 (29.2) | 1.0 (referent) | 29 (15.2) | 28 (14.3) | 1.0 (referent) | |
| B/b | 188 (39.3) | 173 (40.9) | 1.2 (0.8 to 1.8) | 66 (38.0) | 78 (34.0) | 1.0 (0.5 to 2.0) | ||
| b/b | 179 (37.2) | 137 (30.0) | 1.5 (1.0 to 2.3)b | 88 (46.8) | 102 (51.7) | 0.9 (0.5 to 2.0) | ||
| Any b | 367 (76.5) | 310 (70.8) | 1.4 (1.0 to 1.9) | 154 (84.8) | 180 (85.7) | 1.0 (0.5 to 1.8) | ||
| Poly(A) | S/S | Premenopausal | 98 (15.7) | 79 (15.4) | 1.0 (referent) | 23 (9.1) | 14 (6.8) | 1.0 (referent) |
| L/S | 303 (45.3) | 260 (47.3) | 0.9 (0.6 to 1.4) | 109 (39.6) | 88 (39.2) | 0.8 (0.4 to 1.7) | ||
| L/L | 256 (39) | 203 (37.3) | 1.0 (0.7 to 1.5) | 144 (51.3) | 118 (54.1) | 0.7 (0.3 to 1.6) | ||
| Any L | 559 (84.3) | 463 (84.6) | 1.0 (0.7 to 1.4) | 253 (90.9) | 206 (93.3) | 0.7 (0.4 to 1.6) | ||
| S/S | Postmenopausal | 69 (14.5) | 70 (15.8) | 1.0 (referent) | 12 (8.5) | 13 (6.8) | 1.0 (referent) | |
| L/S | 229 (47.2) | 222 (52.2) | 1.0 (0.7 to 1.6) | 72 (41.9) | 81 (38.9) | 0.8 (0.3 to 2.1) | ||
| L/L | 184 (38.3) | 151 (31.9) | 1.3 (0.9 to 2.1) | 81 (49.5) | 103 (54.3) | 0.8 (0.3 to 2.1) | ||
| Any L | 413 (85.5) | 373 (84.2) | 1.2 (0.8 to 1.8) | 153 (91.5) | 184 (93.2) | 0.8 (0.3 to 2.0) | ||
aOdds ratio (OR) adjusted for age, race, study site, and sampling weights. bP for trend <0.05.