Table 5.
Correlation analysis of hypoxia-inducible factor 1α (HIF-1α) expression and standard clinicopathological parameters
| HIF-1α-positive (n = 125) | HIF-1α-negative (n = 91) | P value | |
| Median patient age (years) | 59 | 59 | 0.59 |
| Median tumour size (mm) | 20 | 20 | 0.23 |
| Tumour grade | 0.52 | ||
| 1 | 22 | 15 | |
| 2 | 44 | 22 | |
| 3 | 27 | 23 | |
| Nodal status | 0.02 | ||
| Negative | 62 | 31 | |
| Positive | 63 | 60 | |
| Oestrogen receptor status | 0.90 | ||
| Negative | 98 | 72 | |
| Positive | 27 | 19 | |
| Human epidermal growth factor receptor 2 status | 0.77 | ||
| Negative | 12 | 11 | |
| Positive | 87 | 70 |
n < 216 data not available.