Table 4.
Frequency of outcome death depending on patient characteristics and extrinsic risk factors
| Risk factor | Number (%) of patients | Number (%) of patients with outcome death | P valuea | Relative risk | ||
| Without risk factor | With risk factor | Without risk factor | With risk factor | |||
| Age ≥ median (64 years) | 27 (51.9) | 25 (48.1) | 8 (29.6) | 7 (28.0) | 1.00 | 0.95 |
| Gender, male | 15 (28.8) | 37 (71.2) | 4 (26.7) | 11 (29.7) | 1.00 | 1.12 |
| Simplified Acute Physiology Score > median (31) | 27 (51.9) | 25 (48.1) | 6 (22.2) | 9 (36.0) | 0.36 | 1.62 |
| Time at risk on SICU > median (8.5 days) | 26 (50.0) | 26 (50.0) | 5 (19.2) | 10 (38.5) | 0.22 | 2.00 |
| Ventilation time > median (4.7 days) | 26 (50.0) | 26 (50.0) | 2 (7.7) | 13 (50.0) | 0.002 | 6.50 |
| Bronchoscopy | 24 (46.1) | 28 (53.9) | 3 (12.5) | 12 (42.9) | 0.03 | 3.43 |
| Number of bronchoscopies > median (1) | 37 (71.1) | 15 (28.9) | 10 (27.0) | 5 (33.3) | 0.74 | 1.23 |
| Tracheotomy | 46 (88.5) | 6 (11.5) | 11 (23.9) | 4 (66.7) | 0.05 | 2.79 |
| Reintubation | 37 (71.1) | 15 (28.9) | 10 (27.0) | 5 (33.3) | 0.74 | 1.23 |
| Reanimation | 44 (84.6) | 8 (15.4) | 12 (27.3) | 3 (37.5) | 0.68 | 1.38 |
| Cardiovascular disease | ||||||
| Cardiomyopathyb | 48 (92.3) | 4 (7.7) | 15 (31.3) | 0 (0) | 0.31 | - |
| Valvular heart disease | 35 (67.3) | 17 (32.7) | 11 (31.4) | 4 (23.5) | 0.75 | 0.75 |
| Cystic fibrosisb | 51 (98.1) | 1 (1.9) | 15 (29.4) | 0 (0) | 1.00 | - |
| Infrarenal aortic aneurysm | 47 (90.4) | 5 (9.6) | 13 (27.7) | 2 (40.0) | 0.62 | 1.45 |
| Suprararenal aortic aneurysm | 47 (90.4) | 5 (9.6) | 14 (29.8) | 1 (20.0) | 1.00 | 0.67 |
| Coronary heart disease | 37 (71.1) | 15 (28.9) | 8 (21.6) | 7 (46.7) | 0.10 | 2.16 |
| Congenital valvular heart disease | 48 (92.3) | 4 (7.7) | 14 (29.2) | 1 (25.0) | 1.00 | 0.86 |
| Surgical intervention | ||||||
| Solid organ transplantation | 44 (84.6) | 8 (15.4) | 14 (31.8) | 1 (12.5) | 0.41 | 0.39 |
| Left ventricular assist device | 43 (82.7) | 9 (17.3) | 12 (27.9) | 3 (33.3) | 0.71 | 1.19 |
| Coronary artery bypass graft | 38 (73.1) | 14 (26.9) | 9 (23.7) | 6 (42.9) | 0.19 | 1.81 |
| Aortic surgery | 41 (78.8) | 11 (21.2) | 12 (29.3) | 3 (27.3) | 1.00 | 0.93 |
| Valve surgery | 37 (71.1) | 15 (28.9) | 12 (32.4) | 3 (20.0) | 0.51 | 0.62 |
| Immunosuppression | 27 (51.9) | 25 (48.1) | 9 (33.3) | 6 (24.0) | 0.55 | 0.72 |
| Steroids | 28 (53.8) | 24 (46.2) | 10 (35.7) | 5 (20.8) | 0.36 | 0.58 |
| Cyclosporin | 46 (88.5) | 6 (11.5) | 14 (30.4) | 1 (16.7) | 0.66 | 0.55 |
| Mycophenolate mofetil | 44 (84.6) | 8 (15.4) | 14 (31.8) | 1 (12.5) | 0.41 | 0.39 |
| Basiliximab | 46 (88.5) | 6 (11.5) | 14 (30.4) | 1 (16.7) | 0.66 | 0.55 |
| Tacrolimus | 48 (92.3) | 4 (7.7) | 14 (29.2) | 1 (25.0) | 1.00 | 0.86 |
| Blood productsb | 2 (3.8) | 50 (96.2) | 0 (0) | 15 (30.0) | 1.00 | - |
| Erythrocyte concentrates | 8 (15.4) | 44 (84.6) | 1 (12.5) | 14 (31.8) | 0.41 | 2.55 |
| Fresh frozen plasmab | 4 (7.7) | 48 (92.3) | 0 (0) | 15 (31.3) | 0.31 | - |
| Thrombocyte concentrates | 15 (28.8) | 37 (71.2) | 2 (13.3) | 13 (35.1) | 0.18 | 2.64 |
| Number of erythrocyte concentrates > median (7) | 27 (51.9) | 25 (48.1) | 4 (14.8) | 11 (44.0) | 0.03 | 2.97 |
| Number of fresh frozen plasma units > median (11.5) | 26 (50.0) | 26 (50.0) | 4 (15.4) | 11 (42.3) | 0.06 | 2.75 |
| Number of thrombocyte concentrates > median (3) | 26 (50.0) | 26 (50.0) | 4 (15.4) | 11 (42.3) | 0.06 | 2.75 |
| Clotting factors | 31 (59.6) | 21 (40.4) | 6 (19.4) | 9 (42.9) | 0.12 | 2.21 |
| C1 esterase inhibitor | 49 (94.2) | 3 (5.8) | 13 (26.5) | 2 (66.7) | 0.20 | 2.51 |
| Herpes simplex virus-related tracheobronchitis or pneumoniab | 45 (86.5) | 7 (13.5) | 8 (17.8) | 7 (100) | <0.0001 | - |
| Pneumonia | 46 (88.5) | 6 (11.5) | 11 (23.9) | 4 (66.7) | 0.05 | 2.79 |
aFisher's exact test. bVariable could not be included in the logistic regression model for mathematical reasons.