Table 4.
Foetal deatha among pregnanciesb reported by Trinidadian women by systemic lupus erythematosus (SLE) status
| Early miscarriagea,c (0–12 weeks) | Late miscarriagea,d (13–23 weeks) | All miscarriagea,e (0–23 weeks) | Stillbirthf (≥ 24 weeks) | All foetal deathg | ||||||
| n (%) | Adjusted ORh (95% CI) | n (%) | Adjusted ORh (95% CI) | n (%) | Adjusted ORh (95% CI) | n (%) | Adjusted ORh (95% CI) | n (%) | Adjusted ORh (95% CI) | |
| Mother not diagnosed with SLE | 90 (13.5%) | 1.0 (-) | 9 (1.8%) | 1.0 (-) | 100i (15.0%) | 1.0 (-) | 9 (16.0%) | 1.0 (-) | 109 (16.3%) | 1.0 (-) |
| Mother diagnosed with SLE | 62 (17.6%) | 1.4 (0.6–3.1) | 7 (2.2%) | 1.9 (0.4–9.5) | 73j (20.7%) | 1.6 (0.8–3.5) | 17 (6.2%) | 8.5 (2.5–28.8) | 90j (25.6%) | 2.4 (1.2–4.7) |
| Pregnancy conceived prior to SLE diagnosis | 28 (8.0%) | 1.6 (0.7–3.7) | 3 (1.0%) | 2.2 (0.4–10.9) | 34k (9.7%) | 1.9 (0.8–4.2) | 13 (4.7%) | 8.3 (2.3–29.2) | 47k (13.3%) | 2.6 (1.3–5.4) |
| Pregnancy conceived after SLE diagnosis | 34 (9.7%) | 0.4 (0.1–2.6) | 4 (1.2%) | -l | 39m (11.1%) | 0.3 (0.0–2.5) | 4 (1.4%) | 9.8 (1.7–58.0) | 43m (12.2%) | 1.1 (0.3–3.3) |
aIncludes missed abortions and blighted ova. bAll analyses exclude ectopic and twin pregnancies. cDenominator for all analyses having early (first-trimester) miscarriage as the outcome is all reported pregnancies. dDenominator for all analyses having late (mid-trimester) miscarriage as the outcome is all pregnancies surviving 13 weeks gestation or more. eDenominator for all analyses having all miscarriage as the outcome is all pregnancies. fDenominator for all analyses having stillbirth as the outcome is all live births and stillbirths (excluding miscarriages). gDenominator for all analyses having all foetal death as the outcome is all pregnancies. hAll odds ratios (ORs) adjusted for district of residence, maternal age, pregnancy order and smoking 95% CI, 95% confidence interval. iOne miscarriage has missing gestation; excluded from analyses of early/late miscarriage. jFour miscarriages have missing gestation; excluded from analyses of early/late miscarriage. kThree miscarriages have missing gestation; excluded from analyses of early/late miscarriage. lModel cannot be fitted – all four cases have missing maternal age (strong predictor of miscarriage, which is needed in the model). mOne miscarriage has missing gestation.