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Correlations between mRNA and biological importance. (a) Proteins identified by two-dimensional PAGE/MS [24] correlates with the most highly expressed genes (Chi-squared test for trend in proportions = 251.9, df = 1, p value < 0.0001). (b) Similarly, there is a significant relationship between expression level and essentiality as determined by TraSH [7,26,27] (Chi-squared test for trend in proportions = 161.2, df = 1, p value < 0.0001).
