Table 1.
Rates | Amounts | |||||||
GO* | P† | a-P‡ | No. of genes§ | GO | P | a-P | No. of genes | |
High correlation | ||||||||
Both low level (4-5) | Cell cycle | <E-17 | <0.001 | 159/370 | Cell cycle | <E-7 | 0.001 | 112/300 |
Meiosis | <E -6 | 0.003 | 52/122 | - | ||||
Regulation of physiological process | <E-16 | <0.001 | 204/518 | Regulation of physiological process | <E-10 | <0.001 | 171/459 | |
DNA binding | <E -12 | <0.001 | 88/190 | DNA binding | <E -8 | <0.001 | 66/146 | |
Protein kinase activity | <E -13 | <0.001 | 64/117 | - | ||||
DNA metabolism | <E -11 | <0.001 | 158/422 | DNA metabolism | <E -5 | 0.017 | 39/372 | |
Response to endogenous stimulus | <E -6 | 0.004 | 65/164 | - | ||||
Regulation of transcription | <E -10 | <0.001 | 120/298 | Regulation of transcription | <E -6 | 0.001 | 99/263 | |
- | RNA splicing | <E -6 | 0.002 | 47/103 | ||||
Lipid kinase activity | <E -5 | 0.005 | 8/8 | - | ||||
Both high level (1-2) | Cytosolic ribosome | <E -24 | <0.001 | 93/147 | Cytosolic ribosome | <E -78 | <0.001 | 149/156 |
Protein biosynthesis | <E -15 | <0.001 | 179/439 | Protein biosynthesis | <E -48 | <0.001 | 247/417 | |
Hydrogen ion transporter activity | <E -6 | 0.001 | 25/43 | Hydrogen ion transporter activity | <E -11 | <0.001 | 33/43 | |
- | Carboxylic acid metabolism | <E -18 | <0.001 | 134/258 | ||||
Mitochondrial matrix | <E -7 | 0.001 | 64/150 | - | ||||
Redox activity | <E -8 | <0.001 | 93/228 | Redox activity | <E -17 | <0.001 | 107/197 | |
Mitochondrial ribosome | <E -5 | 0.01 | 36/78 | - | ||||
- | Ribosome biogenesis | <E -14 | <0.001 | 97/182 | ||||
Proteasome complex | <E -8 | <0.001 | 28/43 | Proteasome complex | <E -13 | <0.001 | 36/45 | |
Nucleotide metabolism | <E -5 | 0.044 | 35/79 | Nucleotide metabolism | <E -11 | <0.001 | 49/79 | |
Endoplasmic reticulum | <E -7 | 0.001 | 127/356 | Endoplasmic reticulum | <E -07 | <0.001 | 118/290 | |
Hexose catabolism | <E -5 | 0.007 | 17/26 | Hexose catabolism | <E -06 | 0.005 | 18/26 | |
Protein folding | <E -6 | 0.001 | 33/62 | - | ||||
- | Cell wall | <E -6 | 0.001 | 29/50 | ||||
Low correlation | ||||||||
Low level in RNA (4/5), high in protein (1/2) | Ribosome biogenesis | <E -5 | 0.022 | 24/190 | ||||
Spore wall assembly | <E -6 | 0.006 | 10/35 | |||||
Glycoprotein biosynthesis | <E -5 | 0.01 | 13/66 | |||||
Oxidoreductase activity, acting on the CH-CH group | <E -5 | 0.019 | 5/9 | |||||
Protein amino acid glycosylation | <E -5 | 0.046 | 12/62 | |||||
Low level in protein (4/5), high in RNA (1/2) | - | Membrane | < E -6 | 0.001 | 46/665 | |||
- | Transporter activity | < E -6 | 0.001 | 24/246 | ||||
- | Cell wall | < E -6 | 0.002 | 10/50 | ||||
- | Vacuole | < E -5 | 0.012 | 15/128 |
*Comparisons were done as in Figure 2. Then, the genes corresponding to different levels of correlation were divided into groups according to their expression level and the GOs were searched. Only statistically significant categories are shown. High correlation class includes both very high and high correlation classes from Figure 2b, while the low correlations include both low and very low correlations classes, also from Figure 2b. †Absolute p value. ‡Adjusted p value. §The number of genes shows how many of the genes in the GO category present among the genes analyzed in each pairwise comparison are within the selected quintile.