TABLE 2.

Baseline and treatment sleep latencies for the various drugs expressed as a percent of normal levels

Drug	Reference	Baseline Sleep latency	% Normal	Treatment sleep latency	% Normal	Change	p Level
Codeine	Fry et al. (1)	3.00	15.9	5.80	33.0	2.8	NS
Gamma-hydroxybutyrate	Scrima et al. (2)	1.40	10.4	3.00	22.4	1.6	0.05
Gamma-hydroxybutyrate	Scrima et al. (3)	2.50	18.7	2.80	20.9	0.3	0.07
Ritanscrin	Arends et al. (4)	5.70	42.5	6.30	47.0	0.6	NS
Viloxazine	Godbout et al. (5,6)	7.09	37.5	8.39	47.7	1.3	0.03
Pemoline	Mitler et al. (6)	7.60	40.2	9.40	53.4	1.8	0.05
Modafinil	Billiard et al. (7)	7.06	37.4	9.73	55.3	2.7	0.01
Protriptyline	Mitler et al. (6)	9.28	49.1	9.59	54.5	0.3	NS
Dextroamphetamine	Mitler et al. (6)	6.58	34.8	12.37	70.3	5.8	0.01
Methylphenidate	Mitler et al. (6)	10.43	55.2	14.06	79.9	3.6	0.01

The MSLT normal value is 13.4 min. The MWT normal value is 18.9 and 17.6 for baseline and treatment, respectively (see text for rationales).