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Binding of Ada2a to chromosomes and H4-AcK12 acetylation are impaired by mutations in components of the Iswi-containing NURF remodelling complex. Polytene chromosomes from wild-type (wt), homozygous Iswi2 and heteroallelic Nurf3011/Nurf3013 mutant males were co-stained with 4,6-diamidino-2-phenylindole (blue) and Ada2a, Ada2b, H4-AcK12 or H3-AcK9/14 (red) antibodies, as indicated.
