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Factor X activation by wild-type and mutant VII(a). The activation of 0.1 μM factor X with 100 nM sTF and varying amounts of phospholipid vesicles were determined as described in Materials and Methods. Results for wild-type factor VII(a) (○) and VII(a)-Q10E32 (•) are given for a concentration of 0.06 nM. Values shown are from triplicate experiments.
