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In vitro analyses of GBS Δcfb mutant. The isogenic GBS Δcfb mutant does not differ from the WT parent strain in susceptibility to (A) human whole blood, (B) murine macrophage, or (C) cathelicidin antimicrobial peptide killing. (D) WT GBS and Δcfb mutant are comparable in adherence to and invasion of cultured human brain microvascular endothelial cells.
