Table 1.

Binding affinities (Ki, nM) of various hallucinogenic phenethylamines mentioned in the text at selected central serotonin sites, and estimated hallucinogenic potency and duration of action (following oral administration) in man. Where possible, affinities are listed as determined by competition binding versus an agonist radioligand. Affinities for receptors in the inactive conformation (determined by saturation binding assays versus an antagonist radioligand) are generally lower (higher Ki values) for all compounds, and are indicated in the table by a superscripted asterisk. Dashes in cells denote no data on affinity at that receptor. Full references to the source articles, denoted by superscripted numbers, can be found in the References section.

DRUG	5-HT1A	5-HT2A	5-HT2C	Hallucinogenic potency in man	Duration of action in man
Mescaline	-	20,000 167	-	200 − 400 mg 93	10 − 12 h 93
DOI	3,843 168	0.65 168	5.37 173	1.5 − 3.0 mg 93	16 − 30 h 93
DOM	7,267 169	21.00 170	41.68 171	3.0 − 10 mg 93	14 − 20 h 93
DOB	3,770 172	1.17 168	152.00 170	1.0 − 3.0 mg 93	18 − 30 h 93
2C-T-7	1,170 28,*	120.00 28,*	39.00 28,*	10 − 30 mg 93	8 − 15 h 93