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R*-bound conformation of Gtα(340–350) (yellow) docked to the structure of a GDP-bound form of heterotrimeric Gt (1GOT) showing the predicted effect of R* on Gt conformation. At the top of Gt is the putative R*-interacting surface of the heterotrimer. GDP in the nucleotide binding site of the α subunit is shown in magenta as a space-filling model.
