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Schematic of membrane-bound state of C-terminal colicin E1 channel domain (P190m) as an extended highly helical 2D array. Ten helices are shown, mostly buried in membrane interfacial region. Anchoring hydrophobic helical hairpin is near the C terminus. Except for region near N terminus (18), surface-bound helices are shown buried in interfacial layer, in contrast to those depicted in refs. 18 and 52.
