Table 1.

Forty statistically significant protein peaks are differentially expressed in normal and aneuploid AF samples

				Peak intensity (d)
m/z (a)	Surface array	p-value (b)	AUC (c)	Normal	Aneuploidies	Fold Change
6080	CM10	0.00001	0.918	1.66	9.50	5.7
2876	CM10	0.0006	0.861	6.37	20.96	3.3
15944	IMAC	0.0013	0.838	4.12	1.99	0.5
3023	CM10	0.0015	0.837	10.06	27.88	2.8
7970	IMAC	0.0016	0.833	4.78	2.67	0.6
6194	CM10	0.003	0.817	1.55	9.75	6.3
3903	IMAC	0.0037	0.810	7.85	2.90	0.4
8455	CM10	0.0065	0.793	38.28	26.92	0.7
22214	CM10	0.0065	0.793	0.30	0.16	0.5
9626	IMAC	0.0068	0.790	5.19	3.01	0.6
24720	Q10	0.0079	0.781	0.58	0.48	0.8
9467	IMAC	0.0105	0.776	6.05	4.02	0.7
3173	Q10	0.0118	0.768	4.64	2.04	0.4
18977	IMAC	0.012	0.771	0.61	0.29	0.5
4323	Q10	0.0134	0.763	5.66	9.47	1.7
5655	Q10	0.0134	0.763	5.47	2.92	0.5
14017	IMAC	0.0137	0.767	4.82	2.65	0.5
3184	CM10	0.0151	0.764	2.93	8.41	2.9
3435	IMAC	0.0157	0.762	2.66	9.04	3.4
8660	CM10	0.0172	0.760	4.95	3.00	0.6
9276	IMAC	0.0178	0.757	1.90	4.11	2.2
12289	IMAC	0.0178	0.757	4.97	3.33	0.7
15056	Q10	0.0194	0.750	0.78	1.31	1.7
3383	CM10	0.0196	0.755	7.24	12.71	1.8
13761	IMAC	0.0202	0.752	6.15	4.10	0.7
7655	Q10	0.0245	0.741	4.52	6.56	1.5
14014	Q10	0.0245	0.741	4.56	2.72	0.6
11670	CM10	0.0251	0.744	3.19	1.92	0.6
4954	IMAC	0.0259	0.743	14.73	10.19	0.7
7007	Q10	0.0275	0.737	3.85	1.98	0.5
6892	Q10	0.0308	0.732	4.34	3.26	0.8
8203	Q10	0.0308	0.732	5.80	3.45	0.6
9159	Q10	0.0308	0.732	9.03	7.82	0.9
11314	Q10	0.0344	0.728	6.90	4.10	0.6
8574	IMAC	0.0367	0.729	12.48	7.55	0.6
4519	Q10	0.0472	0.714	1.44	2.27	1.6
4901	Q10	0.0472	0.714	3.61	2.25	0.6
13809	Q10	0.0472	0.714	4.20	2.73	0.6
49297	Q10	0.0472	0.714	0.21	0.16	0.8
11303	CM10	0.0499	0.716	2.62	1.90	0.7

a) m/z: mass/charge ratio of the protein peak.

b) P-values were calculated using parametric Mann-Whitney test.

c) AUC (area under the ROC curve) were calculated using normal amniotic fluids as reference.

d) Averages of peak intensities.