Table 1.

A summary of the anti-angiogenic properties of cheiradone. IC₅₀ values are The mean of three determinations.

Experiment	IC50 value ± SEM (μM)
	BAEC	HDMEC
VEGF-R1 binding	2.9 ± 0.031
VEGF-R2 binding	0.61 ± 0.14
VEGF induced Proliferation	7.8 ± 1.2	7.4 ± 0.74
Effect on VEGF-induced wound healing	7.1 ± 0.77	6.50 ± .0.97
Effect on VEGF-induced migration	7.5 ± 0.92	5.20 ± 0.38
Effect on VEGF-induced tube formation	7.7 ± 1.5	6.0 ± 0.38
Effect on VEGF-induced invasion	6.3 ± 0.31	8.3 ± 1.0
Toxicity MTT	NS	NS
Toxicity Caspase-3	NS	NS

• NS = Overall inhibition is less than 50% and therefore IC₅₀ values cannot be calculated.