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Representation of the interactions of NADP+ and F180 at the coenzyme binding domain of ALD. Panel A was built by using a homology model obtained for ALD and Panel B was obtained by aligning the three-dimensional model generated for ALD with the published structure of ALD to introduce NADP+ into the coenzyme binding site (Di Costanzo et al. 2007). This figure was generated with PyMOL (http://pymol.sourceforge.net/) and Spdbv (http://www.expasy.org/spdbv/).
