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. 2008 Feb;178(2):989–1002. doi: 10.1534/genetics.107.082453

Figure 1.—

Figure 1.—

Characterization of che-12 and dyf-11 mutants. (A) Uptake of FITC by amphid sensory neurons in a wild-type animal. Left, fluorescence image; right, fluorescence and DIC overlay of the same image. Arrow, cell bodies; asterisks, nonspecific pharyngeal staining. (B) A che-12(mn389) mutant showing FITC-uptake defect. (C) dyf-11(mn392) animals also fail to take up FITC. (D) DiI staining pattern of a wild-type animal. (E) che-12(mn389) animals can also take up DiI. (F) dyf-11(mn392) animals fail to take up DiI. (G) Behavioral defects of che-12(mn399) and dyf-11(mn392) mutants. Both mutants fail to chemotax to 0.2 m NaCl and are unable to respond to an osmotic barrier. dyf-11, but not che-12, animals show defects in odortaxis toward 1% isoamyl alcohol and 1% methyl pyrazine. In all figures anterior is up unless otherwise indicated.